Overview of Picked Chemical Compounds and Intermediates
Overview of Picked Chemical Compounds and Intermediates
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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is often an impurity related to bortezomib, a proteasome inhibitor used in the remedy of several myeloma. Its synthesis or examine is very important for making sure the purity and protection of your drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor in the synthesis of abiraterone acetate, a drug Employed in the therapy of prostate cancer by inhibiting androgen production.
Imatinib Intermediate (CAS NO. 152460-ten-one): A essential compound inside the synthesis of imatinib, a drug that targets specific types of cancer, including Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats many cancers including breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): They're intermediates during the synthesis of gemcitabine, an anti-most cancers drug. Their review is vital for optimizing the production approach and ensuring large purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-5): Lapatinib is employed to take 5 care of breast most cancers, and these intermediates are associated with its creation.
Fulvestrant Intermediates: Fulvestrant is an estrogen receptor antagonist Utilized in the cure of breast most cancers. Numerous intermediates help in the synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug efficient in dealing with cancers for instance ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Utilized in the cure of colorectal most cancers and tiny mobile lung cancer.
three-Amino-one-hydroxyadamantane OTAVA-BB1207229 (CAS 702-eighty two-9): This compound is involved in the synthesis of adamantane derivatives, which have several purposes, including antiviral Qualities.
Vildagliptin Intermediates: Used in the production of vildagliptin, an oral drug for sort 2 diabetes that inhibits the enzyme DPP-4 to regulate blood sugar ranges.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is involved in the synthesis of assorted gluconic acid derivatives, that happen to be Employed in foods, pharmaceutical, and industrial programs.
Canagliflozin Intermediate 2: A precursor in the synthesis of canagliflozin, a medication utilized to manage kind 2 diabetes by inhibiting sodium-glucose co-transporter 2 (SGLT2).