Overview of Picked Chemical Compounds and Intermediates
Overview of Picked Chemical Compounds and Intermediates
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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: That is an impurity connected to bortezomib, a proteasome inhibitor Employed in the procedure of many myeloma. Its synthesis or review is critical for ensuring the purity and protection with the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor while in the synthesis of abiraterone acetate, a drug used in the cure of prostate cancer by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-10-one): A crucial compound in the synthesis of imatinib, a drug that targets precise forms of most cancers, which includes chronic myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Utilized in the synthesis of docetaxel, a chemotherapy medication that treats various cancers for example breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are generally intermediates during the synthesis of gemcitabine, an anti-cancer drug. Their analyze is significant for optimizing the production course of action and ensuring substantial purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-five): Lapatinib is used to deal with breast most cancers, and these intermediates are linked to its manufacturing.
Fulvestrant Intermediates: Fulvestrant can be an estrogen receptor antagonist used in the cure of breast most cancers. Various intermediates help in the synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-16-9): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug helpful in treating cancers for example ovarian, breast, and lung most cancers.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Employed in the treatment of colorectal cancer and tiny cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is involved with the synthesis of adamantane derivatives, that have many purposes, which include antiviral properties.
Vildagliptin Androsta-5 Intermediates: Used in the production of vildagliptin, an oral drug for kind 2 diabetes that inhibits the enzyme DPP-four to regulate blood sugar levels.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is involved with the synthesis of varied gluconic acid derivatives, which might be Employed in food items, pharmaceutical, and industrial purposes.
Canagliflozin Intermediate two: A precursor while in the synthesis of canagliflozin, a medication utilised to control sort 2 Lenvatinib Impurity b diabetes by inhibiting sodium-glucose co-transporter two (SGLT2).